Melanotan 1 (Afamelanotide)
Tan-only MC1R agonist.
- Sizes available
- 10mg
- Lab certificate (COA)
- Supplier-published sample
· Research-grade only · Not for human consumption · 21+ ·
Tanning peptide afamelanotide (EU-approved for EPP).
Mechanism · Selective MC1R agonist. EMA approved 2014 (erythropoietic protoporphyria).
Best for. Not for.
Best for
- Erythropoietic protoporphyria (EPP). FDA/EMA approved indication
- MC1R-selective preference (no libido side effect)
- Pigmentation research. Vitiligo Phase 2/3 (Clinuvel)
Not for
- Cosmetic tan outside EPP. The Scenesse FDA label is limited to EPP
- Active melanoma / atypical nevus family history
- Pregnancy (label contraindication)
Mechanism, dose, ramp, risk.
- Mechanism
- Selective MC1R. Tanning without libido side effect.Source · PEPVERA editorial
- Target dose
- 16 mg implant or 1 mg subq daily for 2 weeks.Source · PEPVERA editorial
- Ramp
- Slow.Source · PEPVERA editorial
- Risks
- Moles darken, less nausea than MT-2.Source · PEPVERA editorial
Compared to its siblings.
Melanotan 1 (Afamelanotide)
Tanning peptide afamelanotide (EU-approved for EPP).
Pros
- · FDA Scenesse 2019 (EPP) approval.
- · Less nausea than MT-2.
- · Preferred when no libido side effect desired.
Cons
- · Higher cost (~$25k per Scenesse implant) and harder to procure than MT-2.
- · No libido effect for users seeking dual benefit.
Melanotan 2
Non-selective MC1R + MC4R. Tan, libido, and nausea side effects. Not approved.
Pros
- · Cost-effective
- · Libido side-effect preferred preference
Cons
- · No FDA approval
- · Mole discoloration + nausea stronger
See Melanotan 2 →
COA per supplier
Published, in-house, or shipment-time
Each supplier declares its own HPLC floor and COA policy. The per-supplier verifier appears on the certificate page; refund and shipping terms vary by supplier and are shown on the supplier listing.
Compare 2 suppliers
| Supplier | Price | COA | Ships | |
|---|---|---|---|---|
| Ascension PeptidesUS | $40$4.00/mg · 10mg | Sample COA published | 3 days | |
| Ameano PeptidesUS | $44$4.40/mg · 10mg | Sample COA published | 2 days |
Direct from foundry. Slower than domestic resellers; consistency is the trade. Insulated packaging, tracked from departure to doorstep. Replacement issued on damage.
Week 1–2
16 mg implant or 1 mg subq daily for 2 weeks.
Initiation
Week 3–4
16 mg implant or 1 mg subq daily for 2 weeks.
Signal emerges
Week 5–8
16 mg implant or 1 mg subq daily for 2 weeks.
Hold
Week 9–12
Cycle review
Assess
Draw 20 units.
1 mg = 0.20 mL at 5.00 mg/mL. 10.0 doses per vial.
drive · III · Ascension Peptides
Melanotan 1 (Afamelanotide) · 10mg