MOTS-c
Mitochondrial fire. Fasted.
- Sizes available
- 5mg · 10mg · 20mg · 40mg
- Lab certificate (COA)
- Supplier-published sample
· Research-grade only · Not for human consumption · 21+ ·
Mitochondrial-derived peptide. Exercise mimetic. In the fasted state effect.
Mechanism · 16-Aa mitochondrial DNA-encoded peptide. AMPK + metabolic homeostasis modulator.
Best for. Not for.
Best for
- Exercise mimetic effect users prioritizing
- Fasted-state training users
- Mitochondrial energy recovery goals
Not for
- Active malignancy, pregnancy, or nursing
- No human Phase 2 RCT. Animal/early human only
- Long-term safety is not established
Mechanism, dose, ramp, risk.
- Mechanism
- Mitochondrial-derived peptide. Modulates AMPK and metabolic homeostasis.Source · PEPVERA editorial
- Target dose
- 10 mg / week, single dose pre-fasted training.Source · PEPVERA editorial
- Ramp
- Begin full dose. 12-week cycle.Source · PEPVERA editorial
- Risks
- Mild fatigue on first dose. Hydrate.Source · PEPVERA editorial
Compared to its siblings.
MOTS-c
Mitochondrial-derived peptide. Exercise mimetic. In the fasted state effect.
Pros
- · Targeted mitochondrial mechanism (mt-encoded) versus cytosolic NAD+ pathway.
- · Different mt-derived class than humanin's cytoprotective signal.
Cons
- · Lacks NAD+'s broad commercial-brand availability (Niagen, Basis).
- · Pre-clinical evidence base versus humanin's similar mt-derived research depth.
NAD+
Sirtuin cofactor. NAD+ pathway.
Pros
- · Broad commercial brands
Cons
- · Different mechanism (cytosolic vs mt-encoded)
See NAD+ →
Humanin
Mitochondrial peptide cytoprotective. Bcl-2/Bax.
Pros
- · Similar mt-derived
Cons
- · Pre-clinical only
See Humanin →
COA per supplier
Published, in-house, or shipment-time
Each supplier declares its own HPLC floor and COA policy. The per-supplier verifier appears on the certificate page; refund and shipping terms vary by supplier and are shown on the supplier listing.
Compare 9 suppliers
| Supplier | Price | COA | Ships | |
|---|---|---|---|---|
| Pure Peptide UKUK | $19.5$3.90/mg · 5mg | In-house COA | 4 days | Out of stock |
| Pure Peptide UKUK | $28.96$2.90/mg · 10mg | In-house COA | 4 days | Out of stock |
| Ameano PeptidesUS | $54$5.40/mg · 10mg | Sample COA published | 2 days | |
| Royal PeptidesUS | $60$6.00/mg · 10mg | Sample COA published | 3 days | |
| SwissChemsUS | $69.95$7.00/mg · 10mg | COA with shipment | 3 days | Out of stock |
| Verified PeptidesUS | $77$3.85/mg · 20mg | Sample COA published | 3 days | |
| Ascension PeptidesUS | $79.99$8.00/mg · 10mg | Sample COA published | 3 days | |
| NG PeptidesUS | $80$2.00/mg · 40mg | Sample COA published | 3 days | Out of stock |
| Royal PeptidesUS | $130$3.25/mg · 40mg | Sample COA published | 3 days |
Direct from foundry. Slower than domestic resellers; consistency is the trade. Insulated packaging, tracked from departure to doorstep. Replacement issued on damage.
Week 1–2
10 mg / week, single dose pre-fasted training.
Initiation
Week 3–4
10 mg / week, single dose pre-fasted training.
Signal emerges
Week 5–8
10 mg / week, single dose pre-fasted training.
Hold
Week 9–12
Cycle review
Assess
Draw 20 units.
1 mg = 0.20 mL at 5.00 mg/mL. 10.0 doses per vial.
eternal · I · Ameano Peptides
MOTS-c · 10mg