Methylene Blue (Pharmaceutical)
NICHE · IX

Methylene Blue (Pharmaceutical)

Electron carrier.

From / per milligram
$16.99$1.7/mg · 10MG
Sizes available
10mg
Lab certificate (COA)
Arrives with shipment

· Research-grade only · Not for human consumption · 21+ ·

What is it

Mitochondrial complex IV electron acceptor. Nootropic / mood.

Mechanism · Phenothiazine dye. Mitochondrial complex IV electron transport. Small molecule.

Who

Best for. Not for.

Best for

  • Medical indication for methemoglobinemia (ProvayBlue FDA 2016)
  • Ifosfamide encephalopathy off-label (oncology)
  • Low-dose nootropic / mitochondrial research framing (off-label)
  • Note: small molecule, not a peptide

Not for

  • Users taking SSRIs, SNRIs, or MAOIs (serotonin-syndrome risk; FDA black box)
  • G6PD deficiency (hemolysis)
  • Pregnancy / pregnancy
  • Renal impairment (excretion impact)
  • Users attempting high-dose nootropic use; the therapeutic window is narrow
What it does

Mechanism, dose, ramp, risk.

Mechanism
Mitochondrial electron carrier. Pharmaceutical-grade for research.Source · PEPVERA editorial
Target dose
0.5-2 mg/kg, oral.Source · PEPVERA editorial
Ramp
Daily.Source · PEPVERA editorial
Risks
Serotonin syndrome with SSRIs.Source · PEPVERA editorial
Alternatives

Compared to its siblings.

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Methylene Blue (Pharmaceutical)

Mitochondrial complex IV electron acceptor. Nootropic / mood.

Pros

  • · FDA ProvayBlue 2016 label for methemoglobinemia.
  • · Small-molecule mechanism distinct from humanin and MOTS-c peptide signaling.

Cons

  • · Not a peptide; humanin and MOTS-c offer peptide signaling for users seeking that.
  • · No animal-aging or exercise evidence base comparable to MOTS-c.

Humanin

Mitochondrial-derived peptide. Different mechanism.

Pros

  • · Peptide signaling

Cons

  • · No FDA approval

See Humanin

MOTS-c

Mitochondrial-encoded peptide. Exercise/aging.

Pros

  • · Animal evidence base

Cons

  • · No human FDA trial

See MOTS-c

How we verify

COA per supplier

Published, in-house, or shipment-time

Each supplier declares its own HPLC floor and COA policy. The per-supplier verifier appears on the certificate page; refund and shipping terms vary by supplier and are shown on the supplier listing.

Suppliers

Compare 1 suppliers

SupplierPriceCOAShips
SwissChemsUS$16.99$1.70/mg · 10mgCOA with shipment3 days
❄ COLD-CHAIN · 5–9 DAYS

Direct from foundry. Slower than domestic resellers; consistency is the trade. Insulated packaging, tracked from departure to doorstep. Replacement issued on damage.

Dosing protocol

Week 1–2

0.5-2 mg/kg, oral.

Initiation

Week 3–4

0.5-2 mg/kg, oral.

Signal emerges

Week 5–8

0.5-2 mg/kg, oral.

Hold

Week 9–12

Cycle review

Assess

Reconstitution

Draw 20 units.

1 mg = 0.20 mL at 5.00 mg/mL. 10.0 doses per vial.

niche · IX · SwissChems

Methylene Blue (Pharmaceutical) · 10mg