
Gonadorelin
Synthetic GnRH.
- Sizes available
- —
- Lab certificate (COA)
- Arrives with shipment
· Research-grade only · Not for human consumption · 21+ ·
Synthetic GnRH. Testosterone restart / TRT adjunct.
Mechanism · Synthetic gonadotropin-releasing hormone decapeptide. Pituitary LH/FSH stimulation.
Best for. Not for.
Best for
- TRT adjunct. Testicular size + endogenous LH preservation (off-label)
- Hypothalamic hypogonadism. Lutrelef pulsatile pump (FDA Ferring label specifically)
- Pituitary function testing. Factrel GnRH stimulation test (FDA, Wyeth)
Not for
- Self-administered TRT restart (medical supervision required)
- Hormone-sensitive cancer history
- Pituitary adenoma
- Pregnancy
Mechanism, dose, ramp, risk.
- Mechanism
- Synthetic gonadotropin-releasing hormone. Used in TRT support.Source · PEPVERA editorial
- Target dose
- 100-200 mcg, 2-3x/wk.Source · PEPVERA editorial
- Ramp
- Continuous in TRT context.Source · PEPVERA editorial
- Risks
- Few reports.Source · PEPVERA editorial
Compared to its siblings.
Gonadorelin
Synthetic GnRH. Testosterone restart / TRT adjunct.
Pros
- · FDA Factrel and Lutrelef labels.
- · Pulsatile pump protocol validated for hypothalamic amenorrhea.
- · Lower aromatization risk than high-dose HCG.
Cons
- · Pituitary-level action sits downstream of kisspeptin's hypothalamic site.
- · HCG remains the TRT-adjunct standard with broader off-label consensus.
HCG (Research Grade)
LH analogue (directly testicular). Restart validated.
Pros
- · FDA Pregnyl/Novarel
- · Standard restart protocol
Cons
- · Aromatization risk (high dose)
See HCG (Research Grade) →
Kisspeptin-10
Hypothalamic level (one step upstream).
Pros
- · Upstream physiologic
Cons
- · Imperial College Phase 2 limited to
See Kisspeptin-10 →
COA per supplier
Published, in-house, or shipment-time
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Direct from foundry. Slower than domestic resellers; consistency is the trade. Insulated packaging, tracked from departure to doorstep. Replacement issued on damage.
Week 1–2
100-200 mcg, 2-3x/wk.
Initiation
Week 3–4
100-200 mcg, 2-3x/wk.
Signal emerges
Week 5–8
100-200 mcg, 2-3x/wk.
Hold
Week 9–12
Cycle review
Assess
Draw 20 units.
1 mg = 0.20 mL at 5.00 mg/mL. 10.0 doses per vial.
drive · V
Gonadorelin · 10mg