
HCG (Research Grade)
TRT support.
- Sizes available
- —
- Lab certificate (COA)
- Arrives with shipment
· Research-grade only · Not for human consumption · 21+ ·
Human chorionic gonadotropin. Testosterone + fertility (TRT maintained).
Mechanism · Glycoprotein hormone (placenta). LH-like receptor activation. Testicular function support.
Best for. Not for.
Best for
- TRT adjunct that preserves testicular size and fertility (common off-label standard)
- Anovulatory infertility (Pregnyl/Novarel FDA female infertility label)
- Cryptorchidism (FDA pediatric label)
- Male hypogonadism (FDA Pregnyl label)
Not for
- Prostate / hormone-sensitive cancer history
- Precocious puberty family history
- Self-administered TRT without monitoring (risk of estradiol spike).
- Pregnancy (label contraindication)
Mechanism, dose, ramp, risk.
- Mechanism
- LH analogue. Maintains testicular function during TRT.Source · PEPVERA editorial
- Target dose
- 250-500 IU 2-3x/wk.Source · PEPVERA editorial
- Ramp
- Continuous.Source · PEPVERA editorial
- Risks
- Aromatization at high dose.Source · PEPVERA editorial
Compared to its siblings.
HCG (Research Grade)
Human chorionic gonadotropin. Testosterone + fertility (TRT maintained).
Pros
- · FDA Pregnyl/Novarel approval with 50+ year safety record.
- · Standard TRT restart protocol.
- · Larger evidence base than research-only kisspeptin-10.
Cons
- · Testicular-level action only, no upstream HPG-axis stimulation.
- · Aromatization risk at high dose, unlike gonadorelin.
Gonadorelin
Direct GnRH. Pituitary stimulation (upstream).
Pros
- · FDA Factrel/Lutrelef
Cons
- · HCG is the TRT-adjunct standard
See Gonadorelin →
Kisspeptin-10
Hypothalamic level (top of the HPG axis).
Pros
- · Upstream physiologic
Cons
- · Research-only, Phase 2
See Kisspeptin-10 →
COA per supplier
Published, in-house, or shipment-time
Each supplier declares its own HPLC floor and COA policy. The per-supplier verifier appears on the certificate page; refund and shipping terms vary by supplier and are shown on the supplier listing.
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Direct from foundry. Slower than domestic resellers; consistency is the trade. Insulated packaging, tracked from departure to doorstep. Replacement issued on damage.
Week 1–2
250-500 IU 2-3x/wk.
Initiation
Week 3–4
250-500 IU 2-3x/wk.
Signal emerges
Week 5–8
250-500 IU 2-3x/wk.
Hold
Week 9–12
Cycle review
Assess
Draw 20 units.
0.5 mg = 0.20 mL at 2.50 mg/mL. 10.0 doses per vial.
drive · VI
HCG (Research Grade) · 5mg